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Effects of illicit drug use on adherence to prescribed antiretroviral medication.

The American journal on addictions / American Academy of Psychiatrists in Alcoholism and Addictions. 
2003 Oct-Dec
[Record Source: PubMed]
This exploratory analysis compared adherence to antiretroviral medication on days that illicit drugs were used and on matched abstinence days in twelve subjects who used MEMS caps during participation in a clinical trial. Adherence on drug use days was lower in seven subjects, higher in one, and the same in four. Three subjects maintained 100% adherence despite illicit substance use on studied days. Thus, in a subset of patients, the actions involved in procuring drugs and the acute effects of using them contribute to non-adherence on those specific drug use days, associated with substance abuse. (Am J Addict 2003;12:455-458)
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